Dr. Huybert Groenendaal

Dr. Huybert Groenendaal

As managing partner, Dr. Huybert Groenendaal helps clients using risk analysis modeling techniques in a broad range of consulting projects in fields and industries that, among others, include forecasting, financial risk analysis, project costs estimation, pharmaco-economics, epidemiology, inventory optimization, mining and transportation. Dr. Groenendaal has extensive experience in risk modeling and analysis for business development, financial valuation, R&D portfolios and portfolio evaluations in pharmaceuticals and medical devices.

Dr. Groenendaal teaches a variety of risk analysis training courses including Risk Modeling in Drug Development, Financial Risk Modeling for Pharmaceuticals, Quantitative Risk Analysis, Introduction to Quantitative Project Cost and Schedule Risk Analysis, Corporate Finance Risk Analysis and customized courses at client sites. He also lectures on the use of risk modeling in business, at the executive MBA program at the Leeds School of Business, University of Colorado at Boulder and at the school of Management at the University of Texas at Dallas, and teaches two online risk analysis courses at

Dr. Groenendaal is an adjunct professor at Colorado State University and mentor at the Wharton Customer Analytics Initiative, Wharton School of Business. He has been an invited speaker at numerous international conferences and has published papers in various scientific journals.


2005 PhD: Wageningen University, The Netherlands - Risk Analysis.

2003 MBA: Wharton School of Business, University of Pennsylvania, Philadelphia, PA, U.S.A. - MBA in Finance.

1998 MSc: Wageningen Agricultural University, The Netherlands - Animal Science [Concentration in 'Veterinary Epidemiology' and 'Animal Health Economics' (with hon.)].



2010 – Managing Partner, EpiX Analytics LLC

2006 – Current Adjunct professor, College of Veterinary Medicine and Biomedical Sciences, Colorado State UniversityCollege of Veterinary Medicine and Biomedical Sciences, Colorado State University.

2002 – 2010 Partner and senior risk analysis consultant, EpiX Analytics LLC (formerly Vose Consulting).

1999 – 2001 Associate Researcher, University of Pennsylvania, Veterinary School, Department of clinical studies, Philadelphia, PA, USA.

1998 – 2001 Associate Researcher, Wageningen University, Department of Social Sciences, Farm Management Group, Wageningen, The Netherlands.

Selected Publications

1. Weber, M F, Groenendaal, H. 2012, Effects of infectious young stock on results of certification, surveillance and control programmes for paratuberculosis in dairy herds. Veterinary Microbiology 2012 Jan 27;154(3-4):272-81.

2. Practical Spreadsheet Risk Modeling for Management, Lehman, D, Groenendaal, H and G. Nolder. Chapman and Hall/CRC, September 1, 2011. Hardback textbook, 284 pages. To purchase from Amazon, select

3. Groenendaal H, Bush M, Hodge FL, Dykstra K, Mudd P, Rajapakse A, Zagmutt F, Quantitative Risk Analysis: Improving Decision Making by Quantifying Uncertainty. American Association of Pharmaceutical Scientists Magazine, April 2011

4. Mudd, P.N., Groenendaal, H, Bush, M.A., Schmith, VD. Probabilistic Risk Analysis: Improving Early Drug Development Decision Making. Clinical Pharmacology & Therapeutics. 2010 Dec;88(6):871-5

5. Barkema, H.W., Hesselink, J.W., Mckenna, S.L.B., Benedictus, G., Groenendaal, H., 2010. Global prevalence and economics of infection with Mycobacterium avium subsp. paratuberculosis in ruminants. In: Behr, M.A., Collins, D.M. (Eds.), Paratuberculosis: organism, disease, control. CAB International, pp. 10-21.

6. Saatkamp, Helmut W., Peter M.J.C. van Beek, Ad R. Moen, and Groenendaal, H., 2010, Financial-economic analysis of Bovine Viral Diarrhea Virus control on Dutch dairy herds. Article submitted for publication to Preventive Veterinary Medicine.

7. Groenendaal, H, Marcy L Tarrants and Christophe Armand, 2010, Treatment of Advanced Parkinson's Disease in the United States: A Cost-Utility Model. Clinical Drug Investigation 2010;30(11):789-98. Poster available for download here.

8. Groenendaal, H., and F.J. Zagmutt (2008). “Scenarios analysis of changes in consumption of dairy products due to a hypothetical causal link between Mycobacterium avium subspecies paratuberculosis and Crohn's Disease.” Journal of Dairy Science. J Dairy Sci. 91(8):3245-58

9. Groenendaal H., and C.A. Wolf (2008). “Farm-level Economic Analysis of the US National Johne’s Disease Demonstration Herd Project, Journal of the American Veterinary Medical Association.” JAVMA 233(12): 1852-1858.

10. Weber, M.F., H. Groenendaal, H., J.W. van Roermund,  and M. Nielen (2004). “Simulation of Alternatives for the Dutch Johne's Disease Certification and Monitoring Program.” Preventive Veterinary Medicine 62(1): 1-17.

11. Groenendaal, H., D.T. Galligan, and H. Mulder (2004). “An Economic Spreadsheet model to Determine Optimal Breeding and Replacement Decisions for Dairy Cattle.” Journal of Dairy Science 87:2146-2157.

12. Groenendaal, H., and D.T. Galligan (2003). “Economic consequences of Johne's Disease control programs on mid-size dairy farms in the US.” Journal of the American Veterinary Medical Association.

13. Groenendaal, H., M. Nielen, and J.W. Hesselink (2003). “Development of the Dutch Johne's disease control program supported by a simulation model.” Preventive Veterinary Medicine 60: 69-90.

14. Galligan, D. T., H Groenendaal, JD Ferguson, G Azzaro. Real Options Analysis to evaluate products used in dairy production. J. Dairy Sci. 85:(Supplement 1): 180, 2002.

15. Groenendaal, H., M. Nielen, D.T. Galligan, and J.W. Hesselink (2002). “Johne's disease control: a simulation approach.” Preventive Veterinary Medicine 54: 225-245.

16. Lindberg A., H. Groenendaal, U. Emanuelson, and S. Allenius (2001). “Identification of dams carrying fetuses persistently infected with bovine viral diarrhea (BVD) applying an indirect ELISA.” Preventive Veterinary Medicine 51: 199-214, 2001. 


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Brief History of EpiX Analytics

EpiX Analytics was founded in 2003 in Princeton, NJ under the Vose Consulting name, and among its offerings it included specialized software to perform Monte Carlo simulations. Read More >>